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Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression

Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung adenocarcinoma A549 cells to NiCl(2) for 24 hr significantly increased global levels of trimethylated H3K4 (H3K4me3), a transcriptional activating mark...

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Detalles Bibliográficos
Autores principales: Tchou-Wong, Kam-Meng, Kiok, Kathrin, Tang, Zuojian, Kluz, Thomas, Arita, Adriana, Smith, Phillip R., Brown, Stuart, Costa, Max
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063782/
https://www.ncbi.nlm.nih.gov/pubmed/21455298
http://dx.doi.org/10.1371/journal.pone.0017728