Distinct Roles of Cdc42 in Thymopoiesis and Effector and Memory T Cell Differentiation

Cdc42 of the Rho GTPase family has been implicated in cell actin organization, proliferation, survival, and migration but its physiological role is likely cell-type specific. By a T cell-specific deletion of Cdc42 in mouse, we have recently shown that Cdc42 maintains naïve T cell homeostasis through...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Fukun, Zhang, Shuangmin, Tripathi, Pulak, Mattner, Jochen, Phelan, James, Sproles, Alyssa, Mo, Jun, Wills-Karp, Marsha, Grimes, H. Leighton, Hildeman, David, Zheng, Yi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063799/
https://www.ncbi.nlm.nih.gov/pubmed/21455314
http://dx.doi.org/10.1371/journal.pone.0018002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063799/
https://www.ncbi.nlm.nih.gov/pubmed/21455314
http://dx.doi.org/10.1371/journal.pone.0018002

Ejemplares similares