Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden

The transcription factor nuclear factor kappa B (NF-κB) is activated in human breast cancer tissues and cell lines. However, it is unclear whether NF-κB activation is a consequence of tumor formation or a contributor to tumor development. We developed a doxycycline-inducible mouse model, termed DNMP...

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Detalles Bibliográficos
Autores principales: Connelly, Linda, Barham, Whitney, Onishko, Halina M., Sherrill, Taylor, Chodosh, Lewis A., Blackwell, Timothy S., Yull, Fiona E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063854/
https://www.ncbi.nlm.nih.gov/pubmed/21076466
http://dx.doi.org/10.1038/onc.2010.521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063854/
https://www.ncbi.nlm.nih.gov/pubmed/21076466
http://dx.doi.org/10.1038/onc.2010.521

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