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Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden
The transcription factor nuclear factor kappa B (NF-κB) is activated in human breast cancer tissues and cell lines. However, it is unclear whether NF-κB activation is a consequence of tumor formation or a contributor to tumor development. We developed a doxycycline-inducible mouse model, termed DNMP...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063854/ https://www.ncbi.nlm.nih.gov/pubmed/21076466 http://dx.doi.org/10.1038/onc.2010.521 |