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Transforming growth factor β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM

Recent studies indicate that a subset of cancer cells possessing stem cell properties, referred to as cancer-initiating or cancer stem cells (CSCs), play crucial roles in tumor initiation, metastasis and resistance to anticancer therapies. Transforming growth factor (TGF)-βs and their family members...

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Detalles Bibliográficos
Autores principales: Wang, Yujun, Yu, Yang, Tsuyada, Akihiro, Ren, Xiubao, Wu, Xiwei, Stubblefield, Kandis, Rankin-Gee, Elyse K., Wang, Shizhen Emily
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063856/
https://www.ncbi.nlm.nih.gov/pubmed/21102523
http://dx.doi.org/10.1038/onc.2010.531