Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster

High blood concentration of the N-terminal cleavage product of the B-type natriuretic peptide (NT-proBNP) is strongly associated with cardiac dysfunction and is increasingly used for heart failure diagnosis. To identify genetic variants associated with NT-proBNP level, we performed a genome-wide ass...

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Detalles Bibliográficos
Autores principales: Del Greco M., Fabiola, Pattaro, Cristian, Luchner, Andreas, Pichler, Irene, Winkler, Thomas, Hicks, Andrew A., Fuchsberger, Christian, Franke, Andre, Melville, Scott A., Peters, Annette, Wichmann, H. Erich, Schreiber, Stefan, Heid, Iris M., Krawczak, Michael, Minelli, Cosetta, Wiedermann, Christian J., Pramstaller, Peter P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063986/
https://www.ncbi.nlm.nih.gov/pubmed/21273288
http://dx.doi.org/10.1093/hmg/ddr035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063986/
https://www.ncbi.nlm.nih.gov/pubmed/21273288
http://dx.doi.org/10.1093/hmg/ddr035

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