Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance

OBJECTIVE: Diet-induced obesity (DIO) is linked to peripheral insulin resistance—a major predicament in type 2 diabetes. This study aims to identify the molecular mechanism by which DIO-triggered endoplasmic reticulum (ER) stress promotes hepatic insulin resistance in mouse models. RESEARCH DESIGN A...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryu, Dongryeol, Seo, Woo-Young, Yoon, Young-Sil, Kim, Yo-Na, Kim, Su Sung, Kim, Hye-Jin, Park, Tae-Sik, Choi, Cheol Soo, Koo, Seung-Hoi
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064081/
https://www.ncbi.nlm.nih.gov/pubmed/21357464
http://dx.doi.org/10.2337/db10-1046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064081/
https://www.ncbi.nlm.nih.gov/pubmed/21357464
http://dx.doi.org/10.2337/db10-1046

Ejemplares similares