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Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance

OBJECTIVE: Diet-induced obesity (DIO) is linked to peripheral insulin resistance—a major predicament in type 2 diabetes. This study aims to identify the molecular mechanism by which DIO-triggered endoplasmic reticulum (ER) stress promotes hepatic insulin resistance in mouse models. RESEARCH DESIGN A...

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Detalles Bibliográficos
Autores principales:	Ryu, Dongryeol, Seo, Woo-Young, Yoon, Young-Sil, Kim, Yo-Na, Kim, Su Sung, Kim, Hye-Jin, Park, Tae-Sik, Choi, Cheol Soo, Koo, Seung-Hoi
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064081/ https://www.ncbi.nlm.nih.gov/pubmed/21357464 http://dx.doi.org/10.2337/db10-1046

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