Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue

OBJECTIVE: The fatty acid translocase and scavenger receptor CD36 is important in the recognition and uptake of lipids. Accordingly, we hypothesized that it plays a role in saturated fatty acid–induced macrophage lipid accumulation and proinflammatory activation. RESEARCH DESIGN AND METHODS: In vitr...

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Detalles Bibliográficos
Autores principales: Nicholls, Hayley T., Kowalski, Greg, Kennedy, David J., Risis, Steve, Zaffino, Lee A., Watson, Nadine, Kanellakis, Peter, Watt, Matthew J., Bobik, Alex, Bonen, Arend, Febbraio, Maria, Lancaster, Graeme I., Febbraio, Mark A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064084/
https://www.ncbi.nlm.nih.gov/pubmed/21378177
http://dx.doi.org/10.2337/db10-1353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064084/
https://www.ncbi.nlm.nih.gov/pubmed/21378177
http://dx.doi.org/10.2337/db10-1353

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