Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

OBJECTIVE: Actin cytoskeleton remodeling is known to be involved in glucose-stimulated insulin secretion (GSIS). We have observed glucose-stimulated changes at the β-cell basal membrane similar to focal adhesion remodeling in cell migration. This led us to study the role of two key focal adhesion pr...

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Detalles Bibliográficos
Autores principales: Rondas, Dieter, Tomas, Alejandra, Halban, Philippe A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064088/
https://www.ncbi.nlm.nih.gov/pubmed/21357465
http://dx.doi.org/10.2337/db10-0946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064088/
https://www.ncbi.nlm.nih.gov/pubmed/21357465
http://dx.doi.org/10.2337/db10-0946

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