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Novel Fat Depot–Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

OBJECTIVE: The study objective was to determine the key early mechanisms underlying the beneficial redistribution, function, and inflammatory profile of adipose tissue in 11β-hydroxysteroid dehydrogenase type 1 knockout (11β-HSD1(−/−)) mice fed a high-fat (HF) diet. RESEARCH DESIGN AND METHODS: By f...

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Detalles Bibliográficos
Autores principales: Wamil, Malgorzata, Battle, Jenny H., Turban, Sophie, Kipari, Tiina, Seguret, David, de Sousa Peixoto, Ricardo, Nelson, Yvonne B., Nowakowska, Dominika, Ferenbach, David, Ramage, Lynne, Chapman, Karen E., Hughes, Jeremy, Dunbar, Donald R., Seckl, Jonathan R., Morton, Nicholas M.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064089/
https://www.ncbi.nlm.nih.gov/pubmed/21350084
http://dx.doi.org/10.2337/db10-0830