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Novel Fat Depot–Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice
OBJECTIVE: The study objective was to determine the key early mechanisms underlying the beneficial redistribution, function, and inflammatory profile of adipose tissue in 11β-hydroxysteroid dehydrogenase type 1 knockout (11β-HSD1(−/−)) mice fed a high-fat (HF) diet. RESEARCH DESIGN AND METHODS: By f...
Autores principales: | Wamil, Malgorzata, Battle, Jenny H., Turban, Sophie, Kipari, Tiina, Seguret, David, de Sousa Peixoto, Ricardo, Nelson, Yvonne B., Nowakowska, Dominika, Ferenbach, David, Ramage, Lynne, Chapman, Karen E., Hughes, Jeremy, Dunbar, Donald R., Seckl, Jonathan R., Morton, Nicholas M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064089/ https://www.ncbi.nlm.nih.gov/pubmed/21350084 http://dx.doi.org/10.2337/db10-0830 |
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