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Diet-Induced Adipose Tissue Inflammation and Liver Steatosis Are Prevented by DPP-4 Inhibition in Diabetic Mice

OBJECTIVE: Diet composition alters the metabolic states of adipocytes and hepatocytes in diabetes. The effects of dipeptidyl peptidase-4 (DPP-4) inhibition on adipose tissue inflammation and fatty liver have been obscure. We investigated the extrapancreatic effects of DPP-4 inhibition on visceral fa...

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Detalles Bibliográficos
Autores principales: Shirakawa, Jun, Fujii, Hideki, Ohnuma, Kei, Sato, Koichiro, Ito, Yuzuru, Kaji, Mitsuyo, Sakamoto, Eri, Koganei, Megumi, Sasaki, Hajime, Nagashima, Yoji, Amo, Kikuko, Aoki, Kazutaka, Morimoto, Chikao, Takeda, Eiji, Terauchi, Yasuo
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064098/
https://www.ncbi.nlm.nih.gov/pubmed/21330637
http://dx.doi.org/10.2337/db10-1338