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Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration

OBJECTIVE: Circulating angiogenic progenitor cells (APCs) participate in endothelial repair after arterial injury. Type 2 diabetes is associated with fewer circulating APCs, APC dysfunction, and impaired endothelial repair. We set out to determine whether insulin resistance adversely affects APCs an...

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Detalles Bibliográficos
Autores principales: Kahn, Matthew B., Yuldasheva, Nadira Y., Cubbon, Richard M., Smith, Jessica, Rashid, Sheikh T., Viswambharan, Hema, Imrie, Helen, Abbas, Afroze, Rajwani, Adil, Aziz, Amir, Baliga, Vivek, Sukumar, Piruthivi, Gage, Matthew, Kearney, Mark T., Wheatcroft, Stephen B.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064103/
https://www.ncbi.nlm.nih.gov/pubmed/21317296
http://dx.doi.org/10.2337/db10-1080