Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

OBJECTIVE: Over 30 loci have been associated with risk of type 2 diabetes at genome-wide statistical significance. Genetic risk scores (GRSs) developed from these loci predict diabetes in the general population. We tested if a GRS based on an updated list of 34 type 2 diabetes–associated loci predic...

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Detalles Bibliográficos
Autores principales: Hivert, Marie-France, Jablonski, Kathleen A., Perreault, Leigh, Saxena, Richa, McAteer, Jarred B., Franks, Paul W., Hamman, Richard F., Kahn, Steven E., Haffner, Steven, Meigs, James B., Altshuler, David, Knowler, William C., Florez, Jose C.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064108/
https://www.ncbi.nlm.nih.gov/pubmed/21378175
http://dx.doi.org/10.2337/db10-1119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064108/
https://www.ncbi.nlm.nih.gov/pubmed/21378175
http://dx.doi.org/10.2337/db10-1119

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