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Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program
OBJECTIVE: Over 30 loci have been associated with risk of type 2 diabetes at genome-wide statistical significance. Genetic risk scores (GRSs) developed from these loci predict diabetes in the general population. We tested if a GRS based on an updated list of 34 type 2 diabetes–associated loci predic...
Autores principales: | Hivert, Marie-France, Jablonski, Kathleen A., Perreault, Leigh, Saxena, Richa, McAteer, Jarred B., Franks, Paul W., Hamman, Richard F., Kahn, Steven E., Haffner, Steven, Meigs, James B., Altshuler, David, Knowler, William C., Florez, Jose C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064108/ https://www.ncbi.nlm.nih.gov/pubmed/21378175 http://dx.doi.org/10.2337/db10-1119 |
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