Unmasking Genes in a Type 1 Diabetes–Resistant Mouse Strain That Enhances Pathogenic CD8 T-Cell Responses

OBJECTIVE: Nominally resistant mouse strains such as C57BL/6 (B6) harbor latent type 1 diabetes susceptibility genes uncovered in outcross to disease-susceptible NOD mice. However, identification of possible recessively acting B6-derived susceptibility genes is limited because very few F2 progeny de...

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Detalles Bibliográficos
Autores principales: Driver, John P., Chen, Yi-Guang, Zhang, Weidong, Asrat, Seblewongel, Serreze, David V.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064110/
https://www.ncbi.nlm.nih.gov/pubmed/21307079
http://dx.doi.org/10.2337/db10-0885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064110/
https://www.ncbi.nlm.nih.gov/pubmed/21307079
http://dx.doi.org/10.2337/db10-0885

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