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New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress

[Image: see text] We review the original rationale for the development and the chemistry of a series of new synthetic oleanane triterpenoids (SO), based on oleanolic acid (1) as a starting material. Many of the new compounds that have been made, such as 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic a...

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Detalles Bibliográficos
Autores principales: Sporn, Michael B., Liby, Karen T., Yore, Mark M., Fu, Liangfeng, Lopchuk, Justin M., Gribble, Gordon W.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064114/
https://www.ncbi.nlm.nih.gov/pubmed/21309592
http://dx.doi.org/10.1021/np100826q