MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

In late mitosis and G1, Mcm2-7 are assembled onto replication origins to license them for initiation in the upcoming S phase. After initiation, Mcm2-7 provide helicase activity to unwind DNA at the replication fork. Here we examine the structure of Mcm2-7 on chromatin in Xenopus egg extracts. We sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Gambus, Agnieszka, Khoudoli, Guennadi A., Jones, Richard C., Blow, J. Julian
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
DNA and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064236/
https://www.ncbi.nlm.nih.gov/pubmed/21282109
http://dx.doi.org/10.1074/jbc.M110.199521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064236/
https://www.ncbi.nlm.nih.gov/pubmed/21282109
http://dx.doi.org/10.1074/jbc.M110.199521

Ejemplares similares