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Translocation, switching and gating: potential roles for ATP in long-range communication on DNA by Type III restriction endonucleases

To cleave DNA, the Type III RM (restriction–modification) enzymes must communicate the relative orientation of two recognition sequences, which may be separated by many thousands of base pairs. This long-range interaction requires ATP hydrolysis by a helicase domain, and both active (DNA translocati...

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Detalles Bibliográficos
Autor principal: Szczelkun, Mark D.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064402/
https://www.ncbi.nlm.nih.gov/pubmed/21428945
http://dx.doi.org/10.1042/BST0390589