Structure of human O-GlcNAc transferase and its complex with a peptide substrate

O-GlcNAc transferase (OGT) is an essential mammalian enzyme that couples metabolic status to the regulation of a wide variety of cellular signaling pathways by acting as a nutrient sensor1. OGT catalyzes the transfer of N-acetyl-glucosamine from UDP-GlcNAc to serines and threonines of cytoplasmic, n...

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Detalles Bibliográficos
Autores principales: Lazarus, Michael B., Nam, Yunsun, Jiang, Jiaoyang, Sliz, Piotr, Walker, Suzanne
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064491/
https://www.ncbi.nlm.nih.gov/pubmed/21240259
http://dx.doi.org/10.1038/nature09638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064491/
https://www.ncbi.nlm.nih.gov/pubmed/21240259
http://dx.doi.org/10.1038/nature09638

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