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Immunogenicity Is Not Improved by Increased Antigen Dose or Booster Dosing of Seasonal Influenza Vaccine in a Randomized Trial of HIV Infected Adults

INTRODUCTION: The risk of poor vaccine immunogenicity and more severe influenza disease in HIV necessitate strategies to improve vaccine efficacy. METHODS: A randomized, multi-centered, controlled, vaccine trial with three parallel groups was conducted at 12 CIHR Canadian HIV Trials Network sites. T...

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Detalles Bibliográficos
Autores principales: Cooper, Curtis, Thorne, Anona, Klein, Marina, Conway, Brian, Boivin, Guy, Haase, David, Shafran, Stephen, Zubyk, Wendy, Singer, Joel, Halperin, Scott, Walmsley, Sharon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064575/
https://www.ncbi.nlm.nih.gov/pubmed/21512577
http://dx.doi.org/10.1371/journal.pone.0017758