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Unexpected Long-Term Protection of Adult Offspring Born to High-Fat Fed Dams against Obesity Induced by a Sucrose-Rich Diet

BACKGROUND: Metabolic and endocrine environment during early life is crucial for metabolic imprinting. When dams were fed a high fat diet (HF diet), rat offspring developed hypothalamic leptin resistance with lean phenotype when weaned on a normal diet. Interestingly, when grown on the HF diet, they...

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Detalles Bibliográficos
Autores principales: Couvreur, Odile, Ferezou, Jacqueline, Gripois, Daniel, Serougne, Colette, Crépin, Delphine, Aubourg, Alain, Gertler, Arieh, Vacher, Claire-Marie, Taouis, Mohammed
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064582/
https://www.ncbi.nlm.nih.gov/pubmed/21464991
http://dx.doi.org/10.1371/journal.pone.0018043