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Lineage-Specific Restraint of Pituitary Gonadotroph Cell Adenoma Growth

Although pituitary adenomas are usually benign, unique trophic mechanisms restraining cell proliferation are unclear. As GH-secreting adenomas are associated with p53/p21-dependent senescence, we tested mechanisms constraining non-functioning pituitary adenoma growth. Thirty six gonadotroph-derived...

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Detalles Bibliográficos
Autores principales: Chesnokova, Vera, Zonis, Svetlana, Zhou, Cuiqi, Ben-Shlomo, Anat, Wawrowsky, Kolja, Toledano, Yoel, Tong, Yunguang, Kovacs, Kalman, Scheithauer, Bernd, Melmed, Shlomo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064664/
https://www.ncbi.nlm.nih.gov/pubmed/21464964
http://dx.doi.org/10.1371/journal.pone.0017924