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HER1-Targeted (86)Y-Panitumumab Possesses Superior Targeting Characteristics than (86)Y-Cetuximab for PET Imaging of Human Malignant Mesothelioma Tumors Xenografts
Malignant mesothelioma (MM), a rare form of cancer is often associated with previous exposure to fibrous minerals, such as asbestos. Asbestos exposure increases HER1-activity and expression in pre-clinical models. Additionally, HER1 over-expression is observed in the majority of MM cases. In this st...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064677/ https://www.ncbi.nlm.nih.gov/pubmed/21464917 http://dx.doi.org/10.1371/journal.pone.0018198 |