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Phosphorylation of human Argonaute proteins affects small RNA binding

Argonaute (Ago) proteins are highly conserved between species and constitute a direct-binding platform for small RNAs including short-interfering RNAs (siRNAs), microRNAs (miRNAs) and Piwi interacting RNAs (piRNAs). Small RNAs function as guides whereas Ago proteins are the actual mediators of gene...

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Detalles Bibliográficos
Autores principales: Rüdel, Sabine, Wang, Yanli, Lenobel, René, Körner, Roman, Hsiao, He-Hsuan, Urlaub, Henning, Patel, Dinshaw, Meister, Gunter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064767/
https://www.ncbi.nlm.nih.gov/pubmed/21071408
http://dx.doi.org/10.1093/nar/gkq1032