Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair

MSH6, a key component of the MSH2–MSH6 complex, plays a fundamental role in the repair of mismatched DNA bases. Herein, we report that MSH6 is a novel Ku70-interacting protein identified by yeast two-hybrid screening. Ku70 and Ku86 are two key regulatory subunits of the DNA-dependent protein kinase,...

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Detalles Bibliográficos
Autores principales: Shahi, Ankita, Lee, Jung-Hee, Kang, Yoonsung, Lee, Sung Haeng, Hyun, Jin-Won, Chang, In-Youb, Jun, Jae-Yeoul, You, Ho Jin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064773/
https://www.ncbi.nlm.nih.gov/pubmed/21075794
http://dx.doi.org/10.1093/nar/gkq1095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064773/
https://www.ncbi.nlm.nih.gov/pubmed/21075794
http://dx.doi.org/10.1093/nar/gkq1095

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