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Tertiary contacts control switching of the SAM-I riboswitch

Riboswitches are non-coding RNAs that control gene expression by sensing small molecules through changes in secondary structure. While secondary structure and ligand interactions are thought to control switching, the exact mechanism of control is unknown. Using a novel two-piece assay that competes...

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Detalles Bibliográficos
Autores principales: Hennelly, Scott P., Sanbonmatsu, Karissa Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064774/
https://www.ncbi.nlm.nih.gov/pubmed/21097777
http://dx.doi.org/10.1093/nar/gkq1096