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The AddAB helicase–nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain

The oligomeric state of Superfamily I DNA helicases is the subject of considerable and ongoing debate. While models based on crystal structures imply that a single helicase core domain is sufficient for DNA unwinding activity, biochemical data from several related enzymes suggest that a higher order...

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Detalles Bibliográficos
Autores principales: Yeeles, Joseph T.P., Gwynn, Emma J., Webb, Martin R., Dillingham, Mark S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064778/
https://www.ncbi.nlm.nih.gov/pubmed/21071401
http://dx.doi.org/10.1093/nar/gkq1124