Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

The multistep kinetics through which DNA-binding proteins bind their targets are heavily studied, but relatively little attention has been paid to proteins leaving the double helix. Using single-DNA stretching and fluorescence detection, we find that sequence-neutral DNA-binding proteins Fis, HU and...

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Detalles Bibliográficos
Autores principales: Graham, John S., Johnson, Reid C., Marko, John F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064784/
https://www.ncbi.nlm.nih.gov/pubmed/21097894
http://dx.doi.org/10.1093/nar/gkq1140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064784/
https://www.ncbi.nlm.nih.gov/pubmed/21097894
http://dx.doi.org/10.1093/nar/gkq1140

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