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Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA
The multistep kinetics through which DNA-binding proteins bind their targets are heavily studied, but relatively little attention has been paid to proteins leaving the double helix. Using single-DNA stretching and fluorescence detection, we find that sequence-neutral DNA-binding proteins Fis, HU and...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064784/ https://www.ncbi.nlm.nih.gov/pubmed/21097894 http://dx.doi.org/10.1093/nar/gkq1140 |