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Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus

Pseudouridine at position 55 (Ψ55) in eubacterial tRNA is produced by TruB. To clarify the role of the Ψ55 modification, we constructed a truB gene disruptant (ΔtruB) strain of Thermus thermophilus which is an extreme-thermophilic eubacterium. Unexpectedly, the ΔtruB strain exhibited severe growth r...

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Detalles Bibliográficos
Autores principales: Ishida, Kazuo, Kunibayashi, Takashi, Tomikawa, Chie, Ochi, Anna, Kanai, Tamotsu, Hirata, Akira, Iwashita, Chikako, Hori, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064792/
https://www.ncbi.nlm.nih.gov/pubmed/21097467
http://dx.doi.org/10.1093/nar/gkq1180