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High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach
There are a variety of in vivo and in vitro methods to determine the genome-wide specificity of a particular trans-acting factor. However there is an inherent limitation to these candidate approaches. Most biological studies focus on the regulation of particular genes, which are bound by numerous un...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064794/ https://www.ncbi.nlm.nih.gov/pubmed/21169336 http://dx.doi.org/10.1093/nar/gkq1213 |