Cargando…
Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53
The state of oligomerization of the tumor suppressor p53 is an important factor in its various biological functions. It has a well-defined tetramerization domain, and the protein exists as monomers, dimers and tetramers in equilibrium. The dissociation constants between oligomeric forms are so low t...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064802/ https://www.ncbi.nlm.nih.gov/pubmed/21097469 http://dx.doi.org/10.1093/nar/gkq800 |