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Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells

Although it is well known that RET gene is strongly activated by retinoic acid (RA) in neuroblastoma cells, the mechanisms underlying such activation are still poorly understood. Here we show that a complex series of molecular events, that include modifications of both chromatin and DNA methylation...

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Detalles Bibliográficos
Autores principales: Angrisano, T., Sacchetti, S., Natale, F., Cerrato, A., Pero, R., Keller, S., Peluso, S., Perillo, B., Avvedimento, V. E., Fusco, A., Bruni, C. B., Lembo, F., Santoro, M., Chiariotti, L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064803/
https://www.ncbi.nlm.nih.gov/pubmed/20952403
http://dx.doi.org/10.1093/nar/gkq864