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A distinct first replication cycle of DNA introduced in mammalian cells

Many mutation events in microsatellite DNA sequences were traced to the first embryonic divisions. It was not known what makes the first replication cycles of embryonic DNA different from subsequent replication cycles. Here we demonstrate that an unusual replication mode is involved in the first cyc...

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Detalles Bibliográficos
Autores principales: Chandok, Gurangad S., Kapoor, Kalvin K., Brick, Rachel M., Sidorova, Julia M., Krasilnikova, Maria M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064806/
https://www.ncbi.nlm.nih.gov/pubmed/21062817
http://dx.doi.org/10.1093/nar/gkq903