Ultraconserved cDNA segments in the human transcriptome exhibit resistance to folding and implicate function in translation and alternative splicing

Ultraconservation, defined as perfect human-to-rodent sequence identity at least 200-bp long, is a strong indicator of evolutionary and functional importance and has been explored extensively at the genome level. However, it has not been investigated at the transcript level, where such extreme conse...

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Detalles Bibliográficos
Autores principales: Sathirapongsasuti, J. Fah, Sathira, Nuankanya, Suzuki, Yutaka, Huttenhower, Curtis, Sugano, Sumio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064809/
https://www.ncbi.nlm.nih.gov/pubmed/21062826
http://dx.doi.org/10.1093/nar/gkq949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064809/
https://www.ncbi.nlm.nih.gov/pubmed/21062826
http://dx.doi.org/10.1093/nar/gkq949

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