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An ANN model for the identification of deleterious nsSNPs in tumor suppressor genes

Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occurs approximately every 1000 bases in the overall human population. The non-synonymous SNPs (nsSNPs), lead to amino acid changes in the protein product may account for nearly half of the known genetic varia...

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Detalles Bibliográficos
Autores principales: Chandra, Vinod, Ramakrishnan, Rejimoan, Ramanathan, Shalini
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064852/
https://www.ncbi.nlm.nih.gov/pubmed/21464845