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Regional Context in the Alignment of Biological Sequence Pairs

Sequence divergence derives from either point substitution or indel (insertion or deletion) processes. We investigated the rates of these two processes both in protein and non-protein coding DNA. We aligned sequence pairs using two pair-hidden Markov models (PHMMs) conjoined by one silent state. The...

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Detalles Bibliográficos
Autores principales: Sammut, Raymond, Huttley, Gavin
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064887/
https://www.ncbi.nlm.nih.gov/pubmed/21107551
http://dx.doi.org/10.1007/s00239-010-9409-0