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Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast
The genes encoding ribosomal RNA (rRNA) are the most abundant genes in the eukaryotic genome. They reside in tandem repetitive clusters, in some cases totaling hundreds of copies. Due to their repetitive structure and highly active transcription, the rRNA gene repeats are some of the most fragile si...
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Formato: | Texto |
Lenguaje: | English |
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SP Birkhäuser Verlag Basel
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064901/ https://www.ncbi.nlm.nih.gov/pubmed/21207101 http://dx.doi.org/10.1007/s00018-010-0613-2 |