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Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast

The genes encoding ribosomal RNA (rRNA) are the most abundant genes in the eukaryotic genome. They reside in tandem repetitive clusters, in some cases totaling hundreds of copies. Due to their repetitive structure and highly active transcription, the rRNA gene repeats are some of the most fragile si...

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Detalles Bibliográficos
Autor principal: Kobayashi, Takehiko
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064901/
https://www.ncbi.nlm.nih.gov/pubmed/21207101
http://dx.doi.org/10.1007/s00018-010-0613-2