Evaluating sequence-derived mtDNA length heteroplasmy by amplicon size analysis

Length heteroplasmy (LH) in mitochondrial (mt)DNA is usually observed in homopolymeric tracts and manifest as mixture of various length variants. The generally used difference-coded annotation to report mtDNA haplotypes does not express the degree of LH variation present in a sample, even more so, i...

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Detalles Bibliográficos
Autores principales: Berger, C., Hatzer-Grubwieser, P., Hohoff, C., Parson, W.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064993/
https://www.ncbi.nlm.nih.gov/pubmed/21067985
http://dx.doi.org/10.1016/j.fsigen.2010.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064993/
https://www.ncbi.nlm.nih.gov/pubmed/21067985
http://dx.doi.org/10.1016/j.fsigen.2010.10.002

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