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Evaluating sequence-derived mtDNA length heteroplasmy by amplicon size analysis
Length heteroplasmy (LH) in mitochondrial (mt)DNA is usually observed in homopolymeric tracts and manifest as mixture of various length variants. The generally used difference-coded annotation to report mtDNA haplotypes does not express the degree of LH variation present in a sample, even more so, i...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064993/ https://www.ncbi.nlm.nih.gov/pubmed/21067985 http://dx.doi.org/10.1016/j.fsigen.2010.10.002 |