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In Vitro Selection of Cathepsin E-Activity-Enhancing Peptide Aptamers at Neutral pH

The aspartic protease cathepsin E has been shown to induce apoptosis in cancer cells under physiological conditions. Therefore, cathepsin E-activity-enhancing peptides functioning in the physiological pH range are valuable potential cancer therapeutic candidates. Here, we have used a general in vitr...

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Detalles Bibliográficos
Autores principales: Biyani, Madhu, Futakami, Masae, Kitamura, Koichiro, Kawakubo, Tomoyo, Suzuki, Miho, Yamamoto, Kenji, Nishigaki, Koichi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064998/
https://www.ncbi.nlm.nih.gov/pubmed/21527983
http://dx.doi.org/10.1155/2011/834525