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Alzheimer's Disease and Metals: A Review of the Involvement of Cellular Membrane Receptors in Metallosignalling

Alzheimer's disease (AD) is a debilitating form of dementia. The hallmark protein associated with the disease is the amyloid beta (Aβ) peptide. Aggregation of Aβ has been shown to depend on interactions with metals. The recent studies now demonstrate that metals also play additional important r...

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Detalles Bibliográficos
Autores principales: Amadoruge, Pavithra C., Barnham, Kevin J.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065006/
https://www.ncbi.nlm.nih.gov/pubmed/21461392
http://dx.doi.org/10.4061/2011/542043