Immunogenicity and Protective Efficacy against Murine Tuberculosis of a Prime-Boost Regimen with BCG and a DNA Vaccine Expressing ESAT-6 and Ag85A Fusion Protein

Heterologous prime-boost regimens utilizing BCG as a prime vaccine probably represent the best hope for the development of novel tuberculosis (TB) vaccines. In this study, we examined the immunogenicity and protective efficacy of DNA vaccine (pcD685A) expressing the fusion protein of Ag85A and ESAT-...

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Detalles Bibliográficos
Autores principales: Lu, Jia, Wang, Chun, Zhou, Zhiguang, Zhang, Ying, Cao, Tingting, Shi, Chunwei, Chen, Zhenhua, Chen, Lingxia, Cai, Changxue, Fan, Xionglin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065234/
https://www.ncbi.nlm.nih.gov/pubmed/21461375
http://dx.doi.org/10.1155/2011/617892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065234/
https://www.ncbi.nlm.nih.gov/pubmed/21461375
http://dx.doi.org/10.1155/2011/617892

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