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Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions

BACKGROUND: It has recently been reported by several sources that original (i.e., present in vivo) glioma cell phenotypes or genotypes cannot be maintained in vitro. For example, glioblastoma cell lines presenting EGFR amplification cannot be established. METHODS AND RESULTS: IDH1 sequencing and los...

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Detalles Bibliográficos
Autores principales: Piaskowski, S, Bienkowski, M, Stoczynska-Fidelus, E, Stawski, R, Sieruta, M, Szybka, M, Papierz, W, Wolanczyk, M, Jaskolski, D J, Liberski, P P, Rieske, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065269/
https://www.ncbi.nlm.nih.gov/pubmed/21326241
http://dx.doi.org/10.1038/bjc.2011.27