Activated Kras(G12D) is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

BACKGROUND: Pancreatic cancer (PC) harbours an activated point mutation (Kras(G12D)) in the Kras proto-oncogene that has been demonstrated to promote the development of PC. METHODS: This study was designed to investigate the effect of the oncogenic Kras(G12D) allele on aggressiveness and metastatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Rachagani, S, Senapati, S, Chakraborty, S, Ponnusamy, M P, Kumar, S, Smith, L M, Jain, M, Batra, S K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065271/
https://www.ncbi.nlm.nih.gov/pubmed/21364589
http://dx.doi.org/10.1038/bjc.2011.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065271/
https://www.ncbi.nlm.nih.gov/pubmed/21364589
http://dx.doi.org/10.1038/bjc.2011.31

Ejemplares similares