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Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model
BACKGROUND: It is widely recognised that sorafenib inhibits a range of molecular targets in renal cell carcinoma (RCC). In this study, we aim to use patient-derived RCC xenografts to delineate the angiogenic and non-angiogenic molecular targets of sorafenib therapy for advanced RCC (aRCC). METHODS:...
Autores principales: | , , , , , , |
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Formato: | Texto |
Idioma: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065286/ https://www.ncbi.nlm.nih.gov/pubmed/21407223 http://dx.doi.org/10.1038/bjc.2011.55 |