Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site

Langerin mediates the carbohydrate-dependent uptake of pathogens by Langerhans cells in the first step of antigen presentation to the adaptive immune system. Langerin binds to an unusually diverse number of endogenous and pathogenic cell surface carbohydrates, including mannose-containing O-specific...

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Detalles Bibliográficos
Autores principales: Feinberg, Hadar, Taylor, Maureen E., Razi, Nahid, McBride, Ryan, Knirel, Yuriy A., Graham, Sarah A., Drickamer, Kurt, Weis, William I.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065333/
https://www.ncbi.nlm.nih.gov/pubmed/21112338
http://dx.doi.org/10.1016/j.jmb.2010.11.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065333/
https://www.ncbi.nlm.nih.gov/pubmed/21112338
http://dx.doi.org/10.1016/j.jmb.2010.11.039

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