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Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site
Langerin mediates the carbohydrate-dependent uptake of pathogens by Langerhans cells in the first step of antigen presentation to the adaptive immune system. Langerin binds to an unusually diverse number of endogenous and pathogenic cell surface carbohydrates, including mannose-containing O-specific...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065333/ https://www.ncbi.nlm.nih.gov/pubmed/21112338 http://dx.doi.org/10.1016/j.jmb.2010.11.039 |